Available Sizes: 25μg, 50 μg, 100 μg, 200 μg.
Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface Antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5.
Conjugation
PerCP/Cyanine5.5.
Isotype
Rat IgG2a, κ.
Applications
FCM.
Concentration
0.2 mg/mL.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
21939.