Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81 and CD82.
Host
Mouse.
Species Reactivity
Human.
Synonyms
Bp35, Leukocyte surface Antigen Leu-16, MS4A1, B-lymphocyte surface Antigen B1.
Conjugation
PerCP/Cyanine5.5.
Isotype
Mouse IgG2b, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
931.