Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface Antigens including CD1, CD2, CD3 and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Host
Mouse.
Species Reactivity
Human.
Synonyms
Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45.
Conjugation
PerCP.
Isotype
Mouse IgG2b, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
5788.