Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation Antigen (VEA) and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94 and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte and platelet activation and has a functional role in redirected lysis mediated by activated NK cells.
Host
Mouse.
Species Reactivity
Human.
Synonyms
Early activation Antigen CD69, Activation inducer molecule, AIM, EA1, MLR-3.
Conjugation
PE/Cyanine7.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
969.