Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3 and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen and factor X.
Host
Mouse.
Species Reactivity
Human.
Synonyms
Integrin alpha-M, Itgam, CD11 Antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b.
Conjugation
PE/Cyanine7.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
3684.