AffiAB® PE/Cyanine5 Anti-Mouse CD183/CXCR3 Antibody

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CAT# AFG-DDF-1730
Size: 100 μg

600.00 600.0 USD 600.00

600.00

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Available Sizes: 25μg, 50 μg, 100 μg, 200 μg.


Background

CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Host

Armenian Hamster.

Species Reactivity

Mouse.

Synonyms

C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3.

Conjugation

PE/Cyanine5.

Isotype

Armenian Hamster IgG.

Applications

FCM.

Concentration

0.2 mg/mL.

Buffer

PBS with 0. 05% Proclin300, 1% BSA.

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Gene-ID

12766.