Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70 and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Host
Mouse.
Species Reactivity
Human.
Synonyms
T-lymphocyte activation Antigen CD86, Cd86, Activation B7-2 Antigen, Early T-cell costimulatory molecule 1, ETC-1.
Conjugation
PE/Cyanine5.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
942.