Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6 and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated Antibody production) ; and promotes mast cell proliferation in combination with IL-4.
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
Conjugation
PE.
Isotype
Rat IgG2b, κ.
Applications
ICFCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
16153.