Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
Host
Rat.
Species Reactivity
Human.
Synonyms
Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor.
Conjugation
PE.
Isotype
Rat IgG1, κ.
Applications
ICFCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
3565.