Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages and some tumor cells involved in tumor metastasis and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
Host
Mouse.
Species Reactivity
Human.
Synonyms
GP3A, GPIIIa, ITGB3, Integrin beta-3.
Conjugation
FITC.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
3690.