Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10 and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis and inflammatory skin diseases.
Host
Mouse.
Species Reactivity
Human.
Synonyms
CXCR3, GPR9, CXC-R3, CXCR-3, CKR-L2.
Conjugation
FITC.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
2833.