Available Sizes: 25μg, 100 μg.
Background
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3 and iC4 and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
Host
Mouse.
Species Reactivity
Human.
Synonyms
Complement receptor type 1, CR1, C3b/C4b receptor, CD35, CR1, C3BR.
Conjugation
Biotin.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
0.5 mg/mL.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
1378.