Available Sizes: 20 Tests, 50 Tests, 100 Tests.
Background
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Cytokine receptor common subunit gamma, Il2rg, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132.
Conjugation
PE.
Isotype
N/A.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Gene-ID
N/A.