Available Sizes: 25 μg, 100 μg.
Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Host
Mouse.
Species Reactivity
Human.
Synonyms
T-cell Antigen CD7, CD7, GP40, T-cell leukemia Antigen, T-cell surface Antigen Leu-9, TP41, TP41.
Conjugation
Biotin.
Isotype
N/A.
Applications
FCM.
Concentration
0.5 mg/mL.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Gene-ID
N/A.