Available Sizes: 20 Tests, 50 Tests, 100 Tests.
Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Host
Mouse.
Species Reactivity
Human.
Synonyms
CD27L receptor, T-cell activation Antigen CD27, T14, S152, TNFRSF7.
Conjugation
PercP.
Isotype
N/A.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Gene-ID
N/A.