Available Sizes: 50 μg, 500 μg, 1 mg.
Background
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3 and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b and fibrinogen.
Host
Rat.
Species Reactivity
Human, Mouse.
Synonyms
Integrin alpha-M, Itgam, CD11 Antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b.
Conjugation
None (Purified Antibody-Azide Free/Low endotoxin).
Isotype
Rat IgG2b, κ.
Applications
Neut, Purification, FCM.
Concentration
0.5 mg/mL.
Buffer
0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is less than 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
16409, 3684.