Available Sizes: 50 μg, 500 μg, 1 mg.
Background
CD90. 2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1. 2. It is expressed on hematopoietic stem cells and neurons, all thymocytes and peripheral T cells in Thy1. 2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90. 2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90. 2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90. 2 has been shown to interact with CD45. The 30H12 Antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with Antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 Antigen, CD90.2, Thy-1.2.
Conjugation
None (Purified Antibody-Azide Free/Low endotoxin).
Isotype
Rat IgG2b, κ.
Applications
Depletion, FCM, Apoptosis.
Concentration
0.5 mg/mL.
Buffer
0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is less than 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
21838.