Available Sizes: 50 μg, 500 μg, 1 mg.
Background
NK-1. 1 surface Antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL and 129. Expression of NKR-P1C Antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1. 1 has also been shown to play a role in NK cell activation, IFN-γ production and cytotoxic granule release. NK-1. 1 and DX5 are commonly used as mouse NK cell markers.
Host
Mouse.
Species Reactivity
Mouse.
Synonyms
Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 Antigen-like family member C, Ly-55c, CD161/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c.
Conjugation
None (Purified Antibody-Azide Free/Low endotoxin).
Isotype
Mouse IgG2a, κ.
Applications
Activation, Block, Depletion, FCM.
Concentration
0.5 mg/mL.
Buffer
0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is less than 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
17059.