Available Sizes: 50 μg, 500 μg, 1 mg.
Background
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
Host
Rat.
Species Reactivity
Human.
Synonyms
Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor.
Conjugation
None (Purified Antibody-Azide Free/Low endotoxin).
Isotype
Rat IgG1, κ.
Applications
Neut, ICFCM.
Concentration
0.5 mg/mL.
Buffer
0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is less than 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
3565.