Available Sizes: 50 μg, 500 μg, 1 mg.
Background
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).
Host
Mouse.
Species Reactivity
Human.
Synonyms
Bp50, CDw40, CD40L receptor, TNFRSF5.
Conjugation
None (Purified Antibody-Azide Free/Low endotoxin).
Isotype
Mouse IgG1, κ.
Applications
Stimulation, FA, FCM.
Concentration
0.5 mg/mL.
Buffer
0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is less than 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
958.