AffiAB® AF/LE Purified Anti-Human CD11a Antibody

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CAT# AFG-DDF-0001
Size: 50 μg

353.00 353.0 USD 353.00

353.00

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Available Sizes: 50 μg, 500 μg, 1 mg.


Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).

Host

Mouse.

Species Reactivity

Human.

Synonyms

Integrin alpha-L, LFA-1A, CD11A, ITGAL

Conjugation

None (Purified Antibody-Azide Free/Low endotoxin).

Isotype

Mouse IgG1, κ.

Applications

FA, FCM.

Concentration

0.5 mg/mL.

Buffer

0.2 μm filtered in PBS, pH7. 2. Azide Free (AF) /Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Storage Conditions

Store at 2~8°C. Do not freeze.

Gene-ID

3683.