Overview
AKT1 is a 62 kDa protein and member of the serine/threonine kinase AKT family. AKT1 is also known as Protein Kinase B (PKB) or Rac Protein Kinase Alpha. The Akt family also includes AKT2. Activation of AKT1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. AKT proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase (s), and the activation of AKT1 and AKT2 is inhibited by the PI kinase inhibitor wortmannin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Conjugate
CF488A.
Concentration
0.1 mg/mL.
Storage Buffer
PBS, 0.1% BSA, 0.05% azide.
Product Applications
IHC, FFPE (verified) |WB (verified) .
Storage Temperature
2°C to 8°C.
Stability
Stable at room temperature or 37°C (98°F) for 7 days.