Unraveling the Role of AICDA: Insights from Antibody-Based Studies

AICDA Antibody

An AICDA antibody is a type of protein-specific antibody designed to target activation-induced cytidine deaminase (AICDA). AICDA is an enzyme primarily involved in antibody diversification processes such as somatic hypermutation and class switch recombination within B cells. AICDA antibodies are used in research to detect and study the expression, localization, and function of AICDA in various biological samples, aiding in the understanding of antibody-mediated immune responses and related diseases


  Rigorously validated for performance and consistency across experiments, ensuring reproducible results.


Compatibility with a range of experimental techniques including Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry, providing flexibility in experimental design and analysis.


 Commercially available from reputable suppliers, making them accessible to researchers worldwide.

AICDA antibodies Applications 

Chromatin Immunoprecipitation

AICDA antibodies can be used in ChIP assays to investigate the binding of AICDA to chromatin regions of interest. This technique helps elucidate the genomic targets of AICDA and its role in DNA modification processes such as somatic hypermutation and class switch recombination.

Functional studies

AICDA antibodies can be utilized in functional assays to investigate the biological activities of AICDA, such as its role in antibody diversification processes or its involvement in DNA damage repair pathways. This includes experiments like AICDA knockout/knockdown studies or blocking experiments to assess the functional consequences of AICDA inhibition.


AICDA antibodies allow researchers to visualize the localization and distribution of AICDA within tissues or cells. This enables the study of AICDA expression patterns and its subcellular localization in various physiological and pathological contexts.

Diagnostic and prognostic applications

AICDA antibodies may have diagnostic or prognostic potential in certain diseases where AICDA dysregulation is implicated, such as cancer or autoimmune disorders. Detection of AICDA expression levels in patient samples using immunohistochemistry or other techniques could provide insights into disease progression or prognosis.
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